Phenotypes associated with this allele

• Allele Symbol: Tg(KRT14-cre)40Smr
• Allele Name: transgene insertion 40, Sarah E Millar
• Allele ID: MGI:3046574
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Bmpr1a^tm2Bhr/Bmpr1a^tm2Bhr Tg(KRT14-cre)40Smr/?	involves: 129S7/SvEvBrd * C57BL/6J * SJL/J	MGI:3046633

Genotype
MGI:3046633

cn1

• Allelic Composition: Bmpr1a^tm2Bhr/Bmpr1a^tm2Bhr; Tg(KRT14-cre)40Smr/?
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal tooth morphology ( J:91054 )

absent teeth ( J:91054 )

• complete absence of incisors and molars

mortality/aging

premature death ( J:91054 )

• survive several months

craniofacial

abnormal tooth morphology ( J:91054 )

absent teeth ( J:91054 )

• complete absence of incisors and molars

growth/size/body

abnormal tooth morphology ( J:91054 )

absent teeth ( J:91054 )

• complete absence of incisors and molars

decreased body size ( J:91054 )

integument

abnormal hair growth ( J:91054 )

alopecia ( J:91054 )

• decreased external hair

abnormal hair shaft morphology ( J:91054 )

• shafts usually fail to form in follicles

abnormal nail morphology ( J:91054 )

• abnormal growths under the nails

abnormal hair follicle morphology ( J:91054 )

• wavy

abnormal hair follicle dermal papilla morphology ( J:91054 )

• misshapen and expanded dermal papillae

abnormal hair follicle orientation ( J:91054 )

• misangled

• not as deep into the dermis

small hair follicles ( J:91054 )

abnormal hair follicle regression ( J:91054 )

• failed to undergo regression as late as day 34