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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		l4Jus25
lethal, Chr 4, Justice 25
MGI:3046735
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		l4Jus25/l4Jus25 involves: 129S7/SvEvBrd * C57BL/6 MGI:3846905
hm2
 		l4Jus25/l4Jus25 Not Specified MGI:3047630


Genotype
MGI:3846905
hm1
Allelic
Composition		 l4Jus25/l4Jus25
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Small size and cardiovascular defects in l4Jus25/l4Jus25 embryos

mortality/aging
premature death ( J:148802 )
• surviving mice are unhealthy and die shortly after weaning
postnatal lethality, incomplete penetrance ( J:148802 )
• few mice are observed at weaning

cardiovascular system
pericardial edema ( J:148802 )
• at E10.5

embryo

growth/size/body
decreased embryo size ( J:148802 )

homeostasis/metabolism
pericardial edema ( J:148802 )
• at E10.5




Genotype
MGI:3047630
hm2
Allelic
Composition		 l4Jus25/l4Jus25
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:89098 )
• animals die before P21; stage not determined




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory