About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tbx1tm4(cre/Esr1*)Bld
targeted mutation 4, Antonio Baldini
MGI:3046795
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Tbx1tm4(cre/Esr1*)Bld/Tbx1+ involves: 129P2/OlaHsd * 129S7/SvEvBrd MGI:3641321
cn2
 		Fgf8tm1.4Mrt/Fgf8+
Tbx1tm4(cre/Esr1*)Bld/Tbx1+ 		involves: 129P2/OlaHsd * 129S7/SvEvBrd MGI:3641318
cn3
 		Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tbx1tm4(cre/Esr1*)Bld/Tbx1+ 		involves: 129P2/OlaHsd * 129S7/SvEvBrd MGI:3641319
cn4
 		Fgf8tm1.3Mrt/Fgf8+
Tbx1tm4(cre/Esr1*)Bld/Tbx1+ 		involves: 129P2/OlaHsd * 129S7/SvEvBrd MGI:3641320


Genotype
MGI:3641321
ht1
Allelic
Composition		 Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx1tm4(cre/Esr1*)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system




Genotype
MGI:3641318
cn2
Allelic
Composition		 Fgf8tm1.4Mrt/Fgf8+
Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8tm1.4Mrt mutation (0 available); any Fgf8 mutation (21 available)
Tbx1tm4(cre/Esr1*)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal aortic arch morphology ( J:110620 )
• defects are seen in 78% of fetuses at E18.5 when tamoxifen is administered at E8.5




Genotype
MGI:3641319
cn3
Allelic
Composition		 Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8tm1.3Mrt mutation (1 available); any Fgf8 mutation (21 available)
Fgf8tm1.4Mrt mutation (0 available); any Fgf8 mutation (21 available)
Tbx1tm4(cre/Esr1*)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal aortic arch morphology ( J:110620 )
• defects are seen in 81, 88, and 89% of fetuses at E18.5 when tamoxifen is administered at E7.5, 8.5 or 9.5 respectively




Genotype
MGI:3641320
cn4
Allelic
Composition		 Fgf8tm1.3Mrt/Fgf8+
Tbx1tm4(cre/Esr1*)Bld/Tbx1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8tm1.3Mrt mutation (1 available); any Fgf8 mutation (21 available)
Tbx1tm4(cre/Esr1*)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal aortic arch morphology ( J:110620 )
• defects are seen in 52, 32, and 63% of fetuses at E18.5 when tamoxifen is administered at E7.5, 8.5 or 9.5 respectively




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory