Phenotypes associated with this allele

• Allele Symbol: Igf1sl2^C3H/HeJ
• Allele Name: C3H/HeJ
• Allele ID: MGI:3046884
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Igf1sl2^C3H/HeJ/Igf1sl2^C3H/HeJ	B6.C3H-Igf1sl2^C3H/HeJ	MGI:3664265
hm2	Igf1sl2^C3H/HeJ/Igf1sl2^C3H/HeJ	involves: C3H/HeJ * C57BL/6J	MGI:3046895
ht3	Igf1sl2^C3H/HeJ/Igf1sl2^C57BL/6J	involves: C3H/HeJ * C57BL/6J	MGI:3046896

Genotype
MGI:3664265

hm1

• Allelic Composition: Igf1sl2^C3H/HeJ/Igf1sl2^C3H/HeJ
• Genetic Background: B6.C3H-Igf1sl2^C3H/HeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating total protein level ( J:111677 )

• increased serum IGF-1 levels

• increased skeletal IGF-1 levels

skeleton

increased osteoclast cell number ( J:111677 )

• increased osteoclast number at 16 weeks of age

increased bone mineral density ( J:111677 )

• increased trabecular bone volume fraction

immune system

increased osteoclast cell number ( J:111677 )

• increased osteoclast number at 16 weeks of age

hematopoietic system

increased osteoclast cell number ( J:111677 )

• increased osteoclast number at 16 weeks of age

Genotype
MGI:3046895

hm2

• Allelic Composition: Igf1sl2^C3H/HeJ/Igf1sl2^C3H/HeJ
• Genetic Background: involves: C3H/HeJ * C57BL/6J

homeostasis/metabolism

increased circulating insulin-like growth factor I level ( J:66640 )

• increased serum IGF-1 levels

Genotype
MGI:3046896

ht3

• Allelic Composition: Igf1sl2^C3H/HeJ/Igf1sl2^C57BL/6J
• Genetic Background: involves: C3H/HeJ * C57BL/6J

homeostasis/metabolism

increased circulating total protein level ( J:66640 )

• increased serum IGF-1 levels