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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hprt1tm1(UAS-Bmp4)Bhr
targeted mutation 1, Richard R Behringer
MGI:3046925
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Hprt1tm1(UAS-Bmp4)Bhr/Hprt1+
Tg(Wnt1-GAL4)1Rth/0 		involves: 129S7/SvEvBrd * C57BL/6 MGI:3047259


Genotype
MGI:3047259
cx1
Allelic
Composition		 Hprt1tm1(UAS-Bmp4)Bhr/Hprt1+
Tg(Wnt1-GAL4)1Rth/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm1(UAS-Bmp4)Bhr mutation (0 available); any Hprt1 mutation (1279 available)
Tg(Wnt1-GAL4)1Rth mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, incomplete penetrance ( J:91296 )
• many transgenic embryos die between E11.5 and E12.5

cardiovascular system
hemorrhage ( J:91296 )
• at E11.5 embryos display midbrain hemorrhage

growth/size/body
embryonic growth retardation ( J:91296 )
• by E11.5 embryos are growth retarded

nervous system
exencephaly ( J:91296 )
• at E11.5 embryos display midbrain exencephaly

embryo
embryonic growth retardation ( J:91296 )
• by E11.5 embryos are growth retarded




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory