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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trgc1tm1.2Dhr
targeted mutation 1.2, David H Raulet
MGI:3046956
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trgc1tm1.2Dhr/Trgc1tm1.2Dhr either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6) MGI:3047272


Genotype
MGI:3047272
hm1
Allelic
Composition		 Trgc1tm1.2Dhr/Trgc1tm1.2Dhr
Genetic
Background		 either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trgc1tm1.2Dhr mutation (0 available); any Trgc1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased gamma-delta T cell number ( J:91304 )
• gamma delta T cells (dendritic epidermal T cells) are absent from the skin however normal gamma delta T cell populations are normal in the spleen and intestinal epithelium
• fewer than expected gamma delta T cells are found in the fetal thymus from E15 to E17

hematopoietic system
decreased gamma-delta T cell number ( J:91304 )
• gamma delta T cells (dendritic epidermal T cells) are absent from the skin however normal gamma delta T cell populations are normal in the spleen and intestinal epithelium
• fewer than expected gamma delta T cells are found in the fetal thymus from E15 to E17




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory