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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or8a1btm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3047226
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Or8a1btm2Mom/Or8a1btm2Mom involves: 129P2/OlaHsd * C57BL/6 MGI:3713933


Genotype
MGI:3713933
hm1
Allelic
Composition		 Or8a1btm2Mom/Or8a1btm2Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1btm2Mom mutation (1 available); any Or8a1b mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory bulb development ( J:91160 )
• instead of converging into a glomeruli, axons of the olfactory bulb diverge and innervate widely dispersed glomeruli across the dorsal bulb
• olfactory neurons innervate preferentially OCAM+ glomeruli
abnormal innervation ( J:91160 )
• olfactory neurons innervate preferentially OCAM+ glomeruli
abnormal neuron morphology ( J:91160 )
• instead of converging into a glomeruli, axons of the olfactory bulb diverge and innervate widely dispersed glomeruli across the dorsal bulb

taste/olfaction
abnormal olfaction ( J:91160 )
• mice respond heterogeneously to odorants as measured by calcium imaging traces




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory