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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptprcaptm1Svn
targeted mutation 1, Burkhart Schraven
MGI:3047383
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptprcaptm1Svn/Ptprcaptm1Svn involves: C57BL/6 MGI:3052060


Genotype
MGI:3052060
hm1
Allelic
Composition		 Ptprcaptm1Svn/Ptprcaptm1Svn
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptprcaptm1Svn mutation (0 available); any Ptprcap mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
enlarged lymph nodes ( J:58712 )
• lymph nodes are slightly enlarged and the size increases as mutants age
lymphoid hyperplasia ( J:58712 )
• cell number in lymph nodes is increased 2-fold compared to wild-type however proliferation rates of splenocytes and lymph node cells in not different from wild-type unlike in Ptprcaptm1Tkda homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory