All Phenotypes Kcnk4<tm1Lzd> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnk4^tm1Lzd
targeted mutation 1, Michel Lazdunski
MGI:3050222

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnk4^tm1Lzd/Kcnk4^tm1Lzd	Not Specified	MGI:3050296
cx2	Kcnk10^tm1Fles/Kcnk10^tm1Fles Kcnk2^tm1Lzd/Kcnk2^tm1Lzd Kcnk4^tm1Lzd/Kcnk4^tm1Lzd	B6.Cg-Kcnk2^tm1Lzd Kcnk10^tm1Fles Kcnk4^tm1Lzd	MGI:3836808

Allelic Composition	Kcnk4^tm1Lzd/Kcnk4^tm1Lzd
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk4^tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:91531 )

N	• homozygous mice do not display increased sensitivity to kainic acid- or pentylenetetrazol-induced seizures

Allelic Composition	Kcnk10^tm1Fles/Kcnk10^tm1Fles Kcnk2^tm1Lzd/Kcnk2^tm1Lzd Kcnk4^tm1Lzd/Kcnk4^tm1Lzd
Genetic Background	B6.Cg-Kcnk2^tm1Lzd Kcnk10^tm1Fles Kcnk4^tm1Lzd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk10^tm1Fles mutation (0 available); any Kcnk10 mutation (32 available)
Kcnk2^tm1Lzd mutation (0 available); any Kcnk2 mutation (34 available)
Kcnk4^tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:145944 )

N	• mice exhibit normal hyperpolarization of hypothalamic neurons in response to glucose

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24