All Phenotypes Kcnk4<tm1Lzd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnk4^tm1Lzd
targeted mutation 1, Michel Lazdunski
MGI:3050222

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnk4^tm1Lzd/Kcnk4^tm1Lzd	Not Specified	MGI:3050296
cx2	Kcnk10^tm1Fles/Kcnk10^tm1Fles Kcnk2^tm1Lzd/Kcnk2^tm1Lzd Kcnk4^tm1Lzd/Kcnk4^tm1Lzd	B6.Cg-Kcnk2^tm1Lzd Kcnk10^tm1Fles Kcnk4^tm1Lzd	MGI:3836808

Allelic Composition	Kcnk4^tm1Lzd/Kcnk4^tm1Lzd
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk4^tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:91531 )

N	• homozygous mice do not display increased sensitivity to kainic acid- or pentylenetetrazol-induced seizures

Allelic Composition	Kcnk10^tm1Fles/Kcnk10^tm1Fles Kcnk2^tm1Lzd/Kcnk2^tm1Lzd Kcnk4^tm1Lzd/Kcnk4^tm1Lzd
Genetic Background	B6.Cg-Kcnk2^tm1Lzd Kcnk10^tm1Fles Kcnk4^tm1Lzd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk10^tm1Fles mutation (0 available); any Kcnk10 mutation (32 available)
Kcnk2^tm1Lzd mutation (0 available); any Kcnk2 mutation (34 available)
Kcnk4^tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:145944 )

N	• mice exhibit normal hyperpolarization of hypothalamic neurons in response to glucose

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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