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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kcnk4tm1Lzd
targeted mutation 1, Michel Lazdunski
MGI:3050222
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Kcnk4tm1Lzd/Kcnk4tm1Lzd Not Specified MGI:3050296
cx2
Kcnk10tm1Fles/Kcnk10tm1Fles
Kcnk2tm1Lzd/Kcnk2tm1Lzd
Kcnk4tm1Lzd/Kcnk4tm1Lzd
B6.Cg-Kcnk2tm1Lzd Kcnk10tm1Fles Kcnk4tm1Lzd MGI:3836808


Genotype
MGI:3050296
hm1
Allelic
Composition
Kcnk4tm1Lzd/Kcnk4tm1Lzd
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk4tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• homozygous mice do not display increased sensitivity to kainic acid- or pentylenetetrazol-induced seizures




Genotype
MGI:3836808
cx2
Allelic
Composition
Kcnk10tm1Fles/Kcnk10tm1Fles
Kcnk2tm1Lzd/Kcnk2tm1Lzd
Kcnk4tm1Lzd/Kcnk4tm1Lzd
Genetic
Background
B6.Cg-Kcnk2tm1Lzd Kcnk10tm1Fles Kcnk4tm1Lzd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk10tm1Fles mutation (0 available); any Kcnk10 mutation (32 available)
Kcnk2tm1Lzd mutation (0 available); any Kcnk2 mutation (34 available)
Kcnk4tm1Lzd mutation (0 available); any Kcnk4 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice exhibit normal hyperpolarization of hypothalamic neurons in response to glucose





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory