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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Socs5tm1Wsa
targeted mutation 1, Warren S Alexander
MGI:3050577
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Socs5tm1Wsa/Socs5tm1Wsa involves: C57BL/6 MGI:3051216
hm2
 		Socs5tm1Wsa/Socs5tm1Wsa involves: C57BL/6 * NZB MGI:5301110


Genotype
MGI:3051216
hm1
Allelic
Composition		 Socs5tm1Wsa/Socs5tm1Wsa
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Socs5tm1Wsa mutation (0 available); any Socs5 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:91591 )
• homozygous mutants are viable and fertile with normal immune system morphology and function




Genotype
MGI:5301110
hm2
Allelic
Composition		 Socs5tm1Wsa/Socs5tm1Wsa
Genetic
Background		 involves: C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Socs5tm1Wsa mutation (0 available); any Socs5 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal mammary gland growth during pregnancy ( J:124116 )
• accelerated development
• increased number of lobuloalveolar structures

integument
abnormal mammary gland growth during pregnancy ( J:124116 )
• accelerated development
• increased number of lobuloalveolar structures

reproductive system
abnormal mammary gland growth during pregnancy ( J:124116 )
• accelerated development
• increased number of lobuloalveolar structures




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory