About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr29Hxl3
hemimelic extra toes-like 3
MGI:3051414
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr29Hxl3/Rr29Hxl3 C57BL/6J-Rr29Hxl3 MGI:3051417
hm2
 		Rr29Hxl3/Rr29Hxl3 D2;B6-Rr29Hxl3/Rbrc MGI:3714747
ht3
 		Rr29Hxl3/Rr29+ C57BL/6J-Rr29Hxl3 MGI:3051418


Genotype
MGI:3051417
hm1
Allelic
Composition		 Rr29Hxl3/Rr29Hxl3
Genetic
Background		 C57BL/6J-Rr29Hxl3
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr29Hxl3 mutation (1 available); any Rr29 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
polydactyly ( J:87798 )
• preaxial polydactyly
• supernumerary metacarpals, metatarsals, and digits
• hemimelia caused by shortening of the radius, tibia, and talus
• hindlimbs usually more affected than forelimbs




Genotype
MGI:3714747
hm2
Allelic
Composition		 Rr29Hxl3/Rr29Hxl3
Genetic
Background		 D2;B6-Rr29Hxl3/Rbrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr29Hxl3 mutation (1 available); any Rr29 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
polydactyly ( J:121866 )
• more severe form of preaxial polydactyly than other Shh ENU mutants
• tripharangeal digit 1
abnormal tibia morphology ( J:121866 )
• tibia hemimelia

skeleton
abnormal tibia morphology ( J:121866 )
• tibia hemimelia




Genotype
MGI:3051418
ht3
Allelic
Composition		 Rr29Hxl3/Rr29+
Genetic
Background		 C57BL/6J-Rr29Hxl3
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr29Hxl3 mutation (1 available); any Rr29 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Skeletal phenotypes of Rr29Hx/Rr29Hx and Rr29Hxl3/Shh+ mice

limbs/digits/tail
polydactyly ( J:87798 )
• preaxial polydactyly
• supernumerary metacarpals, metatarsals, and digits
• hemimelia caused by shortening of the radius, tibia, and talus
• hindlimbs usually more affected than forelimbs




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory