About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt12tm1Wwk
targeted mutation 1, Winston W Y Kao
MGI:3051854
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Krt12tm1Wwk/Krt12tm1Wwk involves: 129P2/OlaHsd * NIH Black Swiss MGI:3051899


Genotype
MGI:3051899
hm1
Allelic
Composition		 Krt12tm1Wwk/Krt12tm1Wwk
Genetic
Background		 involves: 129P2/OlaHsd * NIH Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt12tm1Wwk mutation (1 available); any Krt12 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal cornea epithelium morphology ( J:38023 )
• the superficial epithelial cells are swollen, easily removed with gentle brushing, and lack keratin intermediate filaments
decreased cornea epithelium thickness ( J:38023 )
• the corneal epithelium contains about 3 fewer cell layers and the layers present are not firmly attached to the underlying layers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory