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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt12tm1Wwk
targeted mutation 1, Winston W Y Kao
MGI:3051854
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Krt12tm1Wwk/Krt12tm1Wwk involves: 129P2/OlaHsd * NIH Black Swiss MGI:3051899


Genotype
MGI:3051899
hm1
Allelic
Composition		 Krt12tm1Wwk/Krt12tm1Wwk
Genetic
Background		 involves: 129P2/OlaHsd * NIH Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt12tm1Wwk mutation (1 available); any Krt12 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal cornea epithelium morphology ( J:38023 )
• the superficial epithelial cells are swollen, easily removed with gentle brushing, and lack keratin intermediate filaments
decreased cornea epithelium thickness ( J:38023 )
• the corneal epithelium contains about 3 fewer cell layers and the layers present are not firmly attached to the underlying layers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory