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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ciapin1tm1Yzka
targeted mutation 1, Yuzuru Kanakura
MGI:3051894
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ciapin1tm1Yzka/Ciapin1tm1Yzka involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3052333


Genotype
MGI:3052333
hm1
Allelic
Composition
Ciapin1tm1Yzka/Ciapin1tm1Yzka
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ciapin1tm1Yzka mutation (0 available); any Ciapin1 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes begin to die at E12.5 and all are dead by birth
• homozygotes begin to die at E12.5 and all are dead by birth

cardiovascular system
• walls of heart are thinner than normal

embryo

growth/size/body

hematopoietic system
• erythroblasts in the fetal liver are increased in size
• decreased number of erythroblasts in the fetal liver
• half normal number of red blood cells in the periphery
• hematocrit half normal
• hemoglobin content of peripheral blood half normal

liver/biliary system
• fetal livers about 1/3 normal size
• decreased numbers of erythroblasts in the liver
• a large fraction of fetal liver cells are apoptotic





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory