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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dmpktm1Bew
targeted mutation 1, Be Wieringa
MGI:3054407
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dmpktm1Bew/Dmpktm1Bew involves: 129P2/OlaHsd * C57BL/6 MGI:3054415


Genotype
MGI:3054415
hm1
Allelic
Composition		 Dmpktm1Bew/Dmpktm1Bew
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmpktm1Bew mutation (0 available); any Dmpk mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle physiology ( J:33711 , J:43052 )
• mutants do not show any of the expected signs of myotonic dystrophy (J:33711)
• basal intracellular calcium is increased and calcium depolarization response provoked by acetylcholine or KCl are reduced in cultured skeletal muscles from homozygous mutants (J:43052)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory