Phenotypes associated with this allele

• Allele Symbol: Rora^sg-3J
• Allele Name: staggerer 3 Jackson
• Allele ID: MGI:3054679
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rora^sg-3J/Rora^sg-3J	C57BL/6J-Rora^sg-3J/J	MGI:3054680

Genotype
MGI:3054680

hm1

• Allelic Composition: Rora^sg-3J/Rora^sg-3J
• Genetic Background: C57BL/6J-Rora^sg-3J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:87349 )

• mutant mice have difficulty regaining an upright position after falling over

impaired balance ( J:87349 )

• mutant mice have difficulty maintaining an upright position; they lean to the side and eventually fall over

impaired limb coordination ( J:87349 )

• splaying of the hind limbs becomes noticeable when mutants are between 3 and 7 weeks old

growth/size/body

decreased body size ( J:87349 )

nervous system

abnormal cerebellar Purkinje cell layer ( J:87349 )

• standard pathology workup of 5 mice, aged 22-46 days, revealed a disorganized Purkinje cell layer with loss of granule cells