About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		F11rtm1.1Dej
targeted mutation 1.1, Elisabetta Dejana
MGI:3054821
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		F11rtm1.1Dej/F11rtm1.1Dej Not Specified MGI:3054866
cn2
 		F11rtm1Dej/F11rtm1.1Dej
Tg(Tek-cre)1Ywa/0 		Not Specified MGI:3054867


Genotype
MGI:3054866
hm1
Allelic
Composition		 F11rtm1.1Dej/F11rtm1.1Dej
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F11rtm1.1Dej mutation (0 available); any F11r mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal dendritic cell physiology ( J:92592 )
• the migratory ability of the dendritic cells is increased
increased susceptibility to type IV hypersensitivity reaction ( J:92592 )
• exposure to oxazolone induces increased ear swelling in mutants compared to wild-type mice




Genotype
MGI:3054867
cn2
Allelic
Composition		 F11rtm1Dej/F11rtm1.1Dej
Tg(Tek-cre)1Ywa/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F11rtm1.1Dej mutation (0 available); any F11r mutation (31 available)
F11rtm1Dej mutation (0 available); any F11r mutation (31 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:92592 )
N
• dendritic cell migratory ability is not different from control




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory