All Phenotypes Prkaca<tm2Gsm> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prkaca^tm2Gsm
targeted mutation 2, G Stanley McKnight
MGI:3054825

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkaca^tm2Gsm/Prkaca^tm2Gsm	involves: 129X1/SvJ * C57BL/6	MGI:3054827

Allelic Composition	Prkaca^tm2Gsm/Prkaca^tm2Gsm
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkaca^tm2Gsm mutation (1 available); any Prkaca mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

asthenozoospermia ( J:92616 )

• the proportion of motile sperm is reduced especially in the rapid moving subpopulation

male infertility ( J:92616 )

• males but not females are sterile

impaired fertilization ( J:92616 )

• null sperm cannot fertilize zona-intact eggs but can fertilize zona-free eggs

cellular

asthenozoospermia ( J:92616 )

• the proportion of motile sperm is reduced especially in the rapid moving subpopulation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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