Phenotypes associated with this allele

• Allele Symbol: Htr3a^tm1Jul
• Allele Name: targeted mutation 1, David Julius
• Allele ID: MGI:3055155
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Htr3a^tm1Jul/Htr3a^tm1Jul	either: (involves: 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J * DBA/2)	MGI:3055226

Genotype
MGI:3055226

hm1

• Allelic Composition: Htr3a^tm1Jul/Htr3a^tm1Jul
• Genetic Background: either: (involves: 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J * DBA/2)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased chemical nociceptive threshold ( J:92823 )

• behaviors associated with the persistence of formalin induced pain are significantly reduced however acute pain responses are not different from wild-type

• scratching and stretching responses to serotonin injection are reduced

• homozygous mutants are otherwise healthy and fertile with normal motor abilities and responses to acute thermal, mechanical, and chemical pain responses