Phenotypes associated with this allele

• Allele Symbol: Sobp^jc-2J
• Allele Name: Jackson circler 2 Jackson
• Allele ID: MGI:3055292
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sobp^jc-2J/Sobp^jc-2J	B6(129S2)-Sobp^jc-2J/J	MGI:3686592

Genotype
MGI:3686592

hm1

• Allelic Composition: Sobp^jc-2J/Sobp^jc-2J
• Genetic Background: B6(129S2)-Sobp^jc-2J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

circling ( J:113021 )

• homozygous mutant mice exhibit circling behavior, but are able to swim

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:113021 )

• like mice homozygous for the original Jackson circler mutation, homozygous mutant mice respond to click and 32 kHz pure tone stimuli only at high sound pressure; homozygotes display better hearing at 8 and 16 kHz stimuli compared to C57BL/6J-jc/J homozygotes

• the hearing deficit of homozygous mutant mice is not progressive; their hearing threshold at 16 kHz remained stable at 40 dB over a 19-week testing period