Phenotypes associated with this allele

• Allele Symbol: Nrg2^tm1Bus
• Allele Name: targeted mutation 1, Samantha J Busfield
• Allele ID: MGI:3055488
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrg2^tm1Bus/Nrg2^tm1Bus	involves: 129X1/SvJ * C57BL/6	MGI:3055499

Genotype
MGI:3055499

hm1

• Allelic Composition: Nrg2^tm1Bus/Nrg2^tm1Bus
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:92972 )

• 34% loss of homozygotes prior to weaning

growth/size/body

decreased body weight ( J:92972 )

• 35% (7 gr.) lighter from day 6 through day 39

• by four months, body weight is equivalent to wildtype

reproductive system

decreased litter size ( J:92972 )

• homozygote matings produce smaller litters and reduce pup survival