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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sox15tm1Imad
targeted mutation 1, Ibrahim M Adham
MGI:3056078
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sox15tm1Imad/Sox15tm1Imad either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) MGI:3056108


Genotype
MGI:3056108
hm1
Allelic
Composition		 Sox15tm1Imad/Sox15tm1Imad
Genetic
Background		 either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox15tm1Imad mutation (0 available); any Sox15 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal myoblast differentiation ( J:93031 )
• cultured myoblasts show a marked delay in differentiation potential in vitro
impaired skeletal muscle regeneration ( J:93031 )
• skeletal muscle regeneration is attenuated after crush injury to the TA muscle

cellular
abnormal myoblast differentiation ( J:93031 )
• cultured myoblasts show a marked delay in differentiation potential in vitro




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory