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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rad17tm1Maas
targeted mutation 1, Alex Maas
MGI:3056344
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rad17tm1Maas/Rad17tm1Maas involves: 129P2/OlaHsd * C57BL/6 MGI:3056346


Genotype
MGI:3056346
hm1
Allelic
Composition
Rad17tm1Maas/Rad17tm1Maas
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad17tm1Maas mutation (0 available); any Rad17 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• embryos begin to die after E8.5 with no viable embryos found after E11.5

cardiovascular system
• at E11.5 in most embryos heart abnormalities are seen
• at E11.5 bleeding is seen in the rhombencephalon, mesencephalon, prosencephalon, heart, and liver

embryo
• delays and abnormalities in pharyngeal arch development are seen in most embryos at E11.5
• delays and abnormalities in neural tube development are seen including failure to close the head folds in most embryos at E11.5
• at E11.5 embryos have fewer somites

liver/biliary system
• at E11.5 in most embryos liver abnormalities are seen

nervous system
• delays and abnormalities in neural tube development are seen including failure to close the head folds in most embryos at E11.5

craniofacial
• delays and abnormalities in pharyngeal arch development are seen in most embryos at E11.5





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory