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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sfrp2C50F
Cys50Phe
MGI:3056485
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sfrp2C50F/Sfrp2C50F involves: BALB/c * C3H/HeH MGI:3717757
cx2
 		Sfrp2C50F/Sfrp2C50F
Sfrp5Q27stop/Sfrp5Q27stop 		involves: BALB/c * C3H/HeH MGI:3717759


Genotype
MGI:3717757
hm1
Allelic
Composition		 Sfrp2C50F/Sfrp2C50F
Genetic
Background		 involves: BALB/c * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sfrp2C50F mutation (1 available); any Sfrp2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:119228 )
N
• male and female reproductive organs are normal




Genotype
MGI:3717759
cx2
Allelic
Composition		 Sfrp2C50F/Sfrp2C50F
Sfrp5Q27stop/Sfrp5Q27stop
Genetic
Background		 involves: BALB/c * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sfrp2C50F mutation (1 available); any Sfrp2 mutation (30 available)
Sfrp5Q27stop mutation (1 available); any Sfrp5 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal seminiferous tubule morphology ( J:119228 )
• more residual bodies within the seminiferous tubules are present compared to in wild-type mice

limbs/digits/tail
kinked tail ( J:119228 )
• mice have tail kinks of various degrees

endocrine/exocrine glands
abnormal seminiferous tubule morphology ( J:119228 )
• more residual bodies within the seminiferous tubules are present compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory