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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc1a3tm1Wst
targeted mutation 1, Wilhelm Stoffel
MGI:3056511
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc1a3tm1Wst/Slc1a3tm1Wst involves: 129S1/Sv * 129X1/SvJ MGI:3056590
cx2
 		Slc1a1tm1Wst/Slc1a1tm1Wst
Slc1a3tm1Wst/Slc1a3tm1Wst 		involves: 129S1/Sv * 129X1/SvJ MGI:3056592


Genotype
MGI:3056590
hm1
Allelic
Composition		 Slc1a3tm1Wst/Slc1a3tm1Wst
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc1a3tm1Wst mutation (0 available); any Slc1a3 mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal excitatory postsynaptic currents ( J:93201 )
• faster rise times and slower decay was seen for excitatory post synaptic currents in patch clamp recordings made on Purkinje cells of cerebellar slices
prolonged excitatory postsynaptic current decay time ( J:93201 )
• in patch clamp recordings made on Purkinje cells of cerebellar slices
short excitatory postsynaptic current rise time ( J:93201 )
• in patch clamp recordings made on Purkinje cells of cerebellar slices




Genotype
MGI:3056592
cx2
Allelic
Composition		 Slc1a1tm1Wst/Slc1a1tm1Wst
Slc1a3tm1Wst/Slc1a3tm1Wst
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc1a1tm1Wst mutation (0 available); any Slc1a1 mutation (34 available)
Slc1a3tm1Wst mutation (0 available); any Slc1a3 mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nerve conduction ( J:93201 )
• faster rise times and slower decay was seen for excitatory post synaptic currents in patch clamp recordings made on Purkinje cells of cerebellar slices




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory