Phenotypes associated with this allele

• Allele Symbol: Crebbp^tm1.2Ltz
• Allele Name: targeted mutation 1.2, Beat Lutz
• Allele ID: MGI:3056564
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Crebbp^tm1.2Ltz/Crebbp^tm1.2Ltz Tg(Camk2a-cre)T29-1Stl/0	involves: 129P2/OlaHsd * BALB/c * C57BL * C57BL/6J	MGI:4941348

Genotype
MGI:4941348

cn1

• Allelic Composition: Crebbp^tm1.2Ltz/Crebbp^tm1.2Ltz; Tg(Camk2a-cre)T29-1Stl/0
• Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:168984 )

N • mice exhibit normal anxiety levels, fear conditioning, and spatial navigation

abnormal behavior ( J:168984 )

• after 3 consecutive days in the same arena, mice exhibit slightly less locomotor habituation compared with wild-type mice

impaired long-term object recognition memory ( J:168984 )

• mice exhibit impaired long term recognition memory compared with wild-type mice

nervous system

nervous system phenotype ( J:168984 )

N • neuronal viability is normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Rubinstein-Taybi syndrome		DOID:1933	OMIM:180849 OMIM:610543 OMIM:613684	J:168984