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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Angptl4tm1Jig
targeted mutation 1, Jeffrey I Gordon
MGI:3505565
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Angptl4tm1Jig/Angptl4tm1Jig involves: 129/Sv * C57BL/6 MGI:3510553
ht2
 		Angptl4tm1Jig/Angptl4+ involves: 129/Sv * C57BL/6 MGI:3510554


Genotype
MGI:3510553
hm1
Allelic
Composition		 Angptl4tm1Jig/Angptl4tm1Jig
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Angptl4tm1Jig mutation (0 available); any Angptl4 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
decreased total body fat amount ( J:93455 )
• lower increase in total body fat after a 14 day exposure to gut microbiota (10% compared to 55% in wild-type)
abnormal adipose tissue physiology ( J:93455 )
• germ free mutants had 67% higher epididymal fat pad lipoprotein lipase activity than germ free wild-types




Genotype
MGI:3510554
ht2
Allelic
Composition		 Angptl4tm1Jig/Angptl4+
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Angptl4tm1Jig mutation (0 available); any Angptl4 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
decreased total body fat amount ( J:93455 )
• lower increase in total body fat after a 14 day exposure to gut microbiota (33% compared to 55% in wild-type)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory