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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fv4r
host resistance (Friend leukemia virus)
MGI:3505588
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Fv4r/Fv4+ involves: AKR/J * BALB/c * FRG MGI:3505596
cx2
 		Foxn1nu/Foxn1nu
Fv4r/Fv4r 		involves: BALB/c MGI:3505597


Genotype
MGI:3505596
ht1
Allelic
Composition		 Fv4r/Fv4+
Genetic
Background		 involves: AKR/J * BALB/c * FRG
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fv4r mutation (2 available); any Fv4 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Retroviridae infection ( J:5684 , J:5714 )
• does not develop ecotropic virus-induced splenomegaly orfocal lesions on spleen (J:5684)
• almost completely suppresses growth of ecotropic MuLV and MuSv (J:5714)




Genotype
MGI:3505597
cx2
Allelic
Composition		 Foxn1nu/Foxn1nu
Fv4r/Fv4r
Genetic
Background		 involves: BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1nu mutation (43 available); any Foxn1 mutation (106 available)
Fv4r mutation (2 available); any Fv4 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Retroviridae infection ( J:5684 , J:5714 )
• does not develop ecotropic virus-induced splenomegaly or focal lesions on spleen (J:5684)
• almost completely suppresses growth of ecotropic MuLV and MuSv (J:5714)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory