All Phenotypes Gp1bb<tm1Ware> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gp1bb^tm1Ware
targeted mutation 1, Jerry Ware
MGI:3510459

Summary

2 genotypes

Allelic Composition	Gp1bb^tm1Ware/Gp1bb^tm1Ware
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gp1bb^tm1Ware mutation (0 available); any Gp1bb mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

thrombocytopenia ( J:93756 )

• platelet count about 25% of normal levels

increased mean platelet volume ( J:93756 )

• larger platelet size than normal

homeostasis/metabolism

increased bleeding time ( J:93756 )

• mice display a severe bleeding phenotype

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Bernard-Soulier syndrome		DOID:2217	OMIM:231200	J:93756

Allelic Composition	Gp1bb^tm1Ware/Gp1bb⁺
Genetic Background	Not Specified