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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prdm1tm1Nutt
targeted mutation 1, Stephen L Nutt
MGI:3510704
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prdm1tm1Nutt/Prdm1tm1Nutt involves: C57BL/6 MGI:3510954
cx2
 		Clptm1ltm1d(EUCOMM)Wtsi/Clptm1ltm1d(EUCOMM)Wtsi
Prdm1tm1Nutt/Prdm1+ 		involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N MGI:6281129
cx3
 		Itm2cem1Nutt/Itm2cem1Nutt
Prdm1tm1Nutt/Prdm1+ 		involves: C57BL/6 * C57BL/6J MGI:6281134
cx4
 		Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+ 		involves: C57BL/6 * C57BL/6N MGI:6281123


Genotype
MGI:3510954
hm1
Allelic
Composition		 Prdm1tm1Nutt/Prdm1tm1Nutt
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm1tm1Nutt mutation (1 available); any Prdm1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:93944 )
• homozygotes die late in gestation




Genotype
MGI:6281129
cx2
Allelic
Composition		 Clptm1ltm1d(EUCOMM)Wtsi/Clptm1ltm1d(EUCOMM)Wtsi
Prdm1tm1Nutt/Prdm1+
Genetic
Background		 involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N
Cell Lines EPD0460_2_E07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clptm1ltm1d(EUCOMM)Wtsi mutation (0 available); any Clptm1l mutation (34 available)
Prdm1tm1Nutt mutation (1 available); any Prdm1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:265892 )
N
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls




Genotype
MGI:6281134
cx3
Allelic
Composition		 Itm2cem1Nutt/Itm2cem1Nutt
Prdm1tm1Nutt/Prdm1+
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2cem1Nutt mutation (0 available); any Itm2c mutation (19 available)
Prdm1tm1Nutt mutation (1 available); any Prdm1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:265892 )
N
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls




Genotype
MGI:6281123
cx4
Allelic
Composition		 Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+
Genetic
Background		 involves: C57BL/6 * C57BL/6N
Cell Lines DEPD00512_4_E01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plpp5tm1(KOMP)Mbp mutation (0 available); any Plpp5 mutation (12 available)
Prdm1tm1Nutt mutation (1 available); any Prdm1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:265892 )
N
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory