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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Traf3ip2tm1Lix
targeted mutation 1, Xiaoxia Li
MGI:3510783
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Traf3ip2tm1Lix/Traf3ip2tm1.1Lix
Tg(CD19-cre/ERT2)1Cgn/0
involves: 129/Sv * BALB/c MGI:3511174


Genotype
MGI:3511174
cn1
Allelic
Composition
Traf3ip2tm1Lix/Traf3ip2tm1.1Lix
Tg(CD19-cre/ERT2)1Cgn/0
Genetic
Background
involves: 129/Sv * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CD19-cre/ERT2)1Cgn mutation (0 available)
Traf3ip2tm1.1Lix mutation (0 available); any Traf3ip2 mutation (41 available)
Traf3ip2tm1Lix mutation (0 available); any Traf3ip2 mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• this is less severe than in Act1 null mice
• the number of dendritic cells is increased in the spleen, this is less severe than in Act1 null mice
• the total splenic B cell population is increased however the proportions of different B cell stages are the same as in wild-type littermates
• this is less severe than in Act1 null mice
• this is less severe than in Act1 null mice

immune system
• this is less severe than in Act1 null mice
• the number of dendritic cells is increased in the spleen, this is less severe than in Act1 null mice
• the total splenic B cell population is increased however the proportions of different B cell stages are the same as in wild-type littermates
• this is less severe than in Act1 null mice
• this is less severe than in Act1 null mice
• this is less severe than in Act1 null mice

growth/size/body
• this is less severe than in Act1 null mice





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory