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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc3a2tm1Yai
targeted mutation 1, Yasuhiko Ito
MGI:3511126
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc3a2tm1Yai/Slc3a2tm1Yai involves: 129X1/SvJ * C57BL/6 MGI:3511127
cn2
 		Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1Yai 		involves: 129 * C57BL/6 * SJL MGI:3843277


Genotype
MGI:3511127
hm1
Allelic
Composition		 Slc3a2tm1Yai/Slc3a2tm1Yai
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc3a2tm1Yai mutation (0 available); any Slc3a2 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:93968 )
• embryonic lethality occurred between E3.5 and E9.5




Genotype
MGI:3843277
cn2
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1Yai
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (60 available)
Slc3a2tm1.1Mgin mutation (0 available); any Slc3a2 mutation (39 available)
Slc3a2tm1Yai mutation (0 available); any Slc3a2 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG3 level ( J:148000 )
• decrease in antigen specific levels of IgG3
decreased IgM level ( J:148000 )
• decrease in antigen specific levels of IgM

hematopoietic system
decreased IgG3 level ( J:148000 )
• decrease in antigen specific levels of IgG3
decreased IgM level ( J:148000 )
• decrease in antigen specific levels of IgM




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory