Phenotypes associated with this allele

• Allele Symbol: Hyplip2^MRL/MpJ
• Allele Name: MRL/MpJ
• Allele ID: MGI:3511256
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hyplip2^MRL/MpJ/Hyplip2^MRL/MpJ	involves: BALB/cJ * MRL/MpJ	MGI:3511257

Genotype
MGI:3511257

hm1

• Allelic Composition: Hyplip2^MRL/MpJ/Hyplip2^MRL/MpJ
• Genetic Background: involves: BALB/cJ * MRL/MpJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

atherosclerotic lesions ( J:92871 )

• 30-fold increase in atherosclerotic lesions on a high fat diet compared to BALB/cJ

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:92871 )

• 2-fold decrease in HDL cholesterol on a high fat diet compared to BALB/cJ

increased circulating cholesterol level ( J:92871 )

• increased total cholesterol on a CHOW diet compared to BALB/cJ

increased triglyceride level ( J:92871 )

• increaesd triglycerides on a CHOW diet compared to BALB/cJ