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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pou4f1tm1Et
targeted mutation 1, Eric Turner
MGI:3512089
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Pou4f1tm1Et/Pou4f1tm1Nat involves: 129/Sv * 129S4/SvJae * 129S7/SvEvBrd MGI:3718048
cx2
 		Isl1tm1Tmj/Isl1tm1Tmj
Pou4f1tm1Et/Pou4f1tm1Et 		involves: 129 * C57BL/6 MGI:3817489


Genotype
MGI:3718048
ht1
Allelic
Composition		 Pou4f1tm1Et/Pou4f1tm1Nat
Genetic
Background		 involves: 129/Sv * 129S4/SvJae * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou4f1tm1Et mutation (0 available); any Pou4f1 mutation (13 available)
Pou4f1tm1Nat mutation (0 available); any Pou4f1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

vision/eye
vision/eye phenotype ( J:123264 )
N
• no differences are seen in the optic chiasm or tracts at E16.5 or in retinofungal projections at E18.5




Genotype
MGI:3817489
cx2
Allelic
Composition		 Isl1tm1Tmj/Isl1tm1Tmj
Pou4f1tm1Et/Pou4f1tm1Et
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Isl1tm1Tmj mutation (1 available); any Isl1 mutation (36 available)
Pou4f1tm1Et mutation (0 available); any Pou4f1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
embryonic growth arrest ( J:141110 )
• growth arrest occurs about E9.5

nervous system
abnormal brain development ( J:141110 )
• dorsal fore-brain and midbrain are lost due to necrosis at E10.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory