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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tpst2tm1Klm
targeted mutation 1, Kevin L Moore
MGI:3512111
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tpst2tm1Klm/Tpst2tm1Klm involves: 129S6/SvEvTac * 129S7/SvEvBrd MGI:3621972


Genotype
MGI:3621972
hm1
Allelic
Composition		 Tpst2tm1Klm/Tpst2tm1Klm
Genetic
Background		 involves: 129S6/SvEvTac * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tpst2tm1Klm mutation (0 available); any Tpst2 mutation (106 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
abnormal body weight ( J:107617 )
• starting at 3 weeks of age, body weights of male and female homozygotes are about 20% below wild-type littermates; mice attain normal body weights by 10 weeks of age

reproductive system
male infertility ( J:107617 )
• male null animals are infertile




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory