Analysis Tools|
Allele Symbol Allele Name Allele ID |
Smad2tm1.2Mwst targeted mutation 1.2, Michael Weinstein MGI:3512449 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E7.5 homozygous embryos are much smaller compared to wildtype and have the same phenotype as Smad2tm1Cxd homozygotes
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• at E7.5 homozygous embryos are much smaller compared to wildtype and have the same phenotype as Smad2tm1Cxd homozygotes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• about 10% of heterozygotes are external to the yolk sac
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• homozygous embryos die before E11.5
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• three classes of mutant embryos are seen, those consisting of an empty yolk sac, those that have a mass of tissue attached to the distal tip of the yolk sac, and those that have severe midline defects
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mutants are viable with no obvious abnormalities
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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