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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nqo2tm1Bout
targeted mutation 1, Jean A Boutin
MGI:3512531
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nqo2tm1Bout/Nqo2tm1Bout involves: 129S2/SvPas * C57BL/6 MGI:3717916


Genotype
MGI:3717916
hm1
Allelic
Composition
Nqo2tm1Bout/Nqo2tm1Bout
Genetic
Background
involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nqo2tm1Bout mutation (0 available); any Nqo2 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• a significant increase in the latency to fall on the second day of a rotarod test
• mice perform significantly better when presented with the same object in similar context over their wild-type counterparts
• mice demonstrate improved learning abilities by having a shorter latency to locate the hidden platform from days 2 to 4 in the spatial component of the Morris water maze test
• exploration ratio for the novel object shows a significant difference from wild-type





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory