Phenotypes associated with this allele

• Allele Symbol: repro19
• Allele Name: reproductive mutant 19, JAX Reproductive Mutagenesis Program
• Allele ID: MGI:3512910
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	repro19/repro19	B6;C3Fe-repro19/J	MGI:3580115

Genotype
MGI:3580115

hm1

• Allelic Composition: repro19/repro19
• Genetic Background: B6;C3Fe-repro19/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

decreased seminal vesicle weight ( J:92463 )

♂ • seminal glands of mutant males are diminished in weight

decreased testis weight ( J:92463 )

♂ • testes of mutant males are diminished in weight

reproductive system

oligozoospermia ( J:92463 )

♂ • numbers of spermatocytes and spermatogonial cells are depleted, as are those of spermatids in the testis lumen, and the epididymal sperm concentration is low

teratozoospermia ( J:92463 )

♂ • sperm of mutant males have abnormally formed heads and short or absent tails

abnormal sperm motility ( J:92463 )

♂ • motility of mutant sperm is variable

decreased seminal vesicle weight ( J:92463 )

♂ • seminal glands of mutant males are diminished in weight

decreased testis weight ( J:92463 )

♂ • testes of mutant males are diminished in weight

reduced male fertility ( J:92463 )

♂ • sperm from mutant males yield very low success rates when used for in vitro fertilization

homeostasis/metabolism

increased circulating testosterone level ( J:92463 )

increased circulating luteinizing hormone level ( J:92463 )

cellular

oligozoospermia ( J:92463 )

♂ • numbers of spermatocytes and spermatogonial cells are depleted, as are those of spermatids in the testis lumen, and the epididymal sperm concentration is low

teratozoospermia ( J:92463 )

♂ • sperm of mutant males have abnormally formed heads and short or absent tails

abnormal sperm motility ( J:92463 )

♂ • motility of mutant sperm is variable