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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Crhbptm1Afs
targeted mutation 1, Audrey F Seasholtz
MGI:3513042
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Crhbptm1Afs/Crhbptm1Afs involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3513049


Genotype
MGI:3513049
hm1
Allelic
Composition		 Crhbptm1Afs/Crhbptm1Afs
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crhbptm1Afs mutation (1 available); any Crhbp mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal food intake ( J:57963 )
• food intake was reduced in males only
increased anxiety-related response ( J:57963 )
• "anxiogenic" behavior was increased as measure by a variety of tests

growth/size/body
postnatal growth retardation ( J:57963 )
• male weight gain was reduced between 7 and 15 weeks of age whereas female weight gain was normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory