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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mtmr2tm1Abol
targeted mutation 1, Alessandra Bolino
MGI:3513251
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mtmr2tm1Abol/Mtmr2tm1Abol
Tg(Mpz-cre)26Mes/0 		involves: 129S2/SvPas * FVB/N MGI:3513669


Genotype
MGI:3513669
cn1
Allelic
Composition		 Mtmr2tm1Abol/Mtmr2tm1Abol
Tg(Mpz-cre)26Mes/0
Genetic
Background		 involves: 129S2/SvPas * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtmr2tm1Abol mutation (0 available); any Mtmr2 mutation (38 available)
Tg(Mpz-cre)26Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sciatic nerve morphology ( J:94373 )
• sciatic nerves had myelin outfoldings and recurrent loops in similar numbers and location as Mtmr2tm1.1Abol null mice
abnormal myelination ( J:94373 )
• sciatic nerves had myelin outfoldings and recurrent loops in similar numbers and location as Mtmr2tm1.1Abol null mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory