Phenotypes associated with this allele

• Allele Symbol: Scarb1^Chohd1
• Allele Name: dominant hypercholesterolemia 1
• Allele ID: MGI:3513434
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Scarb1^Chohd1/Scarb1^+	C3HeB/FeJ-Scarb1^Chohd1/Ieg	MGI:3513885

Genotype
MGI:3513885

ht1

• Allelic Composition: Scarb1^Chohd1/Scarb1⁺
• Genetic Background: C3HeB/FeJ-Scarb1^Chohd1/Ieg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:94145 )

• mean serum cholesterol is 208 mg/ml and 204 mg/ml with a penetrance of 82% and 62% for male and female mutants, respectively

increased circulating HDL cholesterol level ( J:94145 )

• mean serum HDL cholesterol is 34 mg/ml and 31 mg/ml for male and female mutants, respectively

increased circulating LDL cholesterol level ( J:94145 )

• mean serum LDL cholesterol is 176 mg/ml and 147 mg/ml for male and female mutants, respectively