Phenotypes associated with this allele

• Allele Symbol: Tg(Alb1-HBV)66Bri
• Allele Name: transgene insertion 66, Ralph L Brinster
• Allele ID: MGI:3513825
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Alb1-GP33/H2-K^b)1Hpi/0 Tg(Alb1-HBV)66Bri/0	involves: C57BL/6 * C57BL/10 * DBA/2	MGI:4838100
cx2	Tg(Alb1-GP33/H2-K^b)1Hpi/0 Tg(Alb1-HBV)66Bri/0 Tg(TcrLCMV)318Sdz/0	involves: C57BL/6 * C57BL/10 * DBA/2	MGI:4838101

Genotype
MGI:4838100

cx1

• Allelic Composition: Tg(Alb1-GP33/H2-K^b)1Hpi/0; Tg(Alb1-HBV)66Bri/0
• Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

liver inflammation ( J:162605 )

• in response to the adoptive transfer of Tg(TcrLCMV)318Sdz T cell cells followed by LCMV infection

liver/biliary system

liver inflammation ( J:162605 )

• in response to the adoptive transfer of Tg(TcrLCMV)318Sdz T cell cells followed by LCMV infection

homeostasis/metabolism

increased circulating alanine transaminase level ( J:162605 )

• in response to the adoptive transfer of Tg(TcrLCMV)318Sdz T cell cells followed by LCMV infection

Genotype
MGI:4838101

cx2

• Allelic Composition: Tg(Alb1-GP33/H2-K^b)1Hpi/0; Tg(Alb1-HBV)66Bri/0; Tg(TcrLCMV)318Sdz/0
• Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2

immune system

liver inflammation ( J:162605 )

• only weak signs of hepatitis (less than 100 U/L) after LCMV infection

liver/biliary system

liver inflammation ( J:162605 )

• only weak signs of hepatitis (less than 100 U/L) after LCMV infection