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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rgs14tm1Pngr
targeted mutation 1, Josef M Penninger
MGI:3514019
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rgs14tm1Pngr/Rgs14tm1Pngr either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1) MGI:3514021


Genotype
MGI:3514021
hm1
Allelic
Composition		 Rgs14tm1Pngr/Rgs14tm1Pngr
Genetic
Background		 either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgs14tm1Pngr mutation (0 available); any Rgs14 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:94516 )
• mutants do not develop past the 1 cell stage

embryo
failure of zygotic cell division ( J:94516 )
• microtubule networks are misaligned or asymmetrical, the nuclei become disorganized and blebbed, and mutants fail to complete the first cell division




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory