Allele Symbol Allele Name Allele ID |
Nodaltm6Rob targeted mutation 6, Elizabeth J Robertson MGI:3521719 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• the density of trabeculae is decreased compared to controls in 4/12 mutants
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• in 4/12 mutants the compact myocardial layer is thinner
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• heart looping is reversed in less than 2% of mutants
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• cardiac morphogenesis is delayed
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• a common atrium is seen in 3/12 mutants at E13.5
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• at E13.5 ventricular septal wall formation is incomplete in about 42% of mutants
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• partial right isomerism is seen in 4% of mutant embryos
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• the density of trabeculae is decreased compared to controls in 4/12 mutants
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• in 4/12 mutants the compact myocardial layer is thinner
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• partial right isomerism is seen in 4% of mutant embryos
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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