Phenotypes associated with this allele

• Allele Symbol: Cntn2^tm2Furl
• Allele Name: targeted mutation 2, Andrew Furley
• Allele ID: MGI:3521785
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cntn2^tm2Furl/Cntn2^tm2Furl	C57BL/6-Cntn2^tm2Furl	MGI:3832885

Genotype
MGI:3832885

hm1

• Allelic Composition: Cntn2^tm2Furl/Cntn2^tm2Furl
• Genetic Background: C57BL/6-Cntn2^tm2Furl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal somatic nervous system physiology ( J:137627 )

• cultured dorsal root ganglion cells have much less repulsion to ventral spinal cord explants than controls

• the level of repulsion is similar to what is observed in sensory neuron axons from L1cam null homozygotes but is less than that observed for neurons from Cntn2^tm1Furl null homozygotes

• in culture, E13.5 sensory axons are refractory to repulsion mediated by Semaphorin-3A