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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gucy2dtm1Sdm
targeted mutation 1, Steven D Munger
MGI:3521821
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gucy2dtm1Sdm/Gucy2dtm1Sdm involves: 129S1/Sv * 129X1/SvJ MGI:3723601


Genotype
MGI:3723601
hm1
Allelic
Composition		 Gucy2dtm1Sdm/Gucy2dtm1Sdm
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gucy2dtm1Sdm mutation (0 available); any Gucy2d mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory bulb periglomerular cell morphology ( J:124965 )
• tyrosine hydrolase immunoreactivity is nearly absent in olfactory bulb periglomular cells whereas TH immunoreactivity is present in all beta-galactosidase positive cell in heterozygotes

taste/olfaction
abnormal olfactory system physiology ( J:124965 )
• as measured by electroolfactogram, uroguanylin- and guanylin-evoked potentials are abolished




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory