Analysis Tools|
Allele Symbol Allele Name Allele ID |
Cacng4tm1Frk targeted mutation 1, Wayne N Frankel MGI:3521945 |
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| Summary |
7 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• viable and fertile; no nervous system or behavioral abnormalities were observed including ataxia, subtle movement disorders, seizure activity or in either ERG or ABR recordings
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• average spike wave discharge duration was 4.8 +/- 4.6 seconds
• average number of spike wave discharges per hour was 37.4 +/- 32.1
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• occasional runting was noted; most evident between 2 and 10 weeks of age
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• average spike wave discharge duration was 4.8 +/- 4.6 seconds
• average number of spike wave discharges per hour was 37.4 +/- 32.1
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• average spike wave discharge duration was 2.3 +/- 1.4 seconds
• average number of spike wave discharges per hour was 24.6 +/- 24.9
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• occasional runting was noted; most evident between 2 and 10 weeks of age
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• average spike wave discharge duration was 2.3 +/- 1.4 seconds
• average number of spike wave discharges per hour was 24.6 +/- 24.9
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• average spike wave discharge duration was 3.9 +/- 4.5 seconds
• average number of spike wave discharges per hour was 48.6 +/- 29.6
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• average spike wave discharge duration was 3.9 +/- 4.5 seconds
• average number of spike wave discharges per hour was 48.6 +/- 29.6
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• average spike wave discharge duration was 1.8 +/- 0.5 seconds
• average number of spike wave discharges per hour was 0.3 +/- 0.7
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• average spike wave discharge duration was 1.8 +/- 0.5 seconds
• average number of spike wave discharges per hour was 0.3 +/- 0.7
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• most mice that survive birth die before 4 weeks of age
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• incomplete penetrance; very few mutant mice survive to birth
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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