Phenotypes associated with this allele

• Allele Symbol: Tg(Gfap-cre)73.12Mvs
• Allele Name: transgene insertion 73.12, Michael V Sofroniew
• Allele ID: MGI:3522215
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rai1^tm2.1Luo/Rai1^tm2.1Luo Tg(Gfap-cre)73.12Mvs/?	either: (involves: 129S1/Sv * BALB/c * C57BL/6 * C57BL/6NHsd) or (involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NHsd)	MGI:5817666
cn2	Smo^tm2Amc/Smo^tm2Amc Tg(Gfap-cre)73.12Mvs/0	involves: 129X1/SvJ * BALB/c * C57BL/6NHsd	MGI:4838615

Genotype
MGI:5817666

cn1

• Allelic Composition: Rai1^tm2.1Luo/Rai1^tm2.1Luo; Tg(Gfap-cre)73.12Mvs/?
• Genetic Background: either: (involves: 129S1/Sv * BALB/c * C57BL/6 * C57BL/6NHsd) or (involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NHsd)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:237687 )

• mice do not exhibit differences in behavior, motor function or body weight

Genotype
MGI:4838615

cn2

• Allelic Composition: Smo^tm2Amc/Smo^tm2Amc; Tg(Gfap-cre)73.12Mvs/0
• Genetic Background: involves: 129X1/SvJ * BALB/c * C57BL/6NHsd

nervous system

nervous system phenotype ( J:165495 )

N • mice exhibit normal forebrain morphology and cytoarchitecture

N • the number of astrocytes in the cortex is normal

astrocytosis ( J:165495 )

• mild in the cortex