All Phenotypes Kcnn2<tm1.1Jpad> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnn2^tm1.1Jpad
targeted mutation 1.1, John P Adelman
MGI:3522425

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnn2^tm1.1Jpad/Kcnn2^tm1.1Jpad	Not Specified	MGI:3527278

Allelic Composition	Kcnn2^tm1.1Jpad/Kcnn2^tm1.1Jpad
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn2^tm1.1Jpad mutation (1 available); any Kcnn2 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal action potential ( J:187145 )

• prior to and after apamin treated dopamine neurons exhibit a higher mean inter-spike interval compared with wild-type neurons

abnormal afterhyperpolarization ( J:94941 )

• the apamin sensitive component of the medium afterhyperpolarization current is absent from CA1 neurons, however hippocampal morphology and slow afterhyperpolarization currents are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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