Phenotypes associated with this allele

• Allele Symbol: Avpr1b^tm1Wsy
• Allele Name: targeted mutation 1, W Scott Young III
• Allele ID: MGI:3522438
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Avpr1b^tm1Wsy/Avpr1b^tm1Wsy	involves: 129S4/SvJae * C57BL/6	MGI:3522583

Genotype
MGI:3522583

hm1

• Allelic Composition: Avpr1b^tm1Wsy/Avpr1b^tm1Wsy
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased aggression ( J:94939 )

• males display a longer latency to attack and less agonistic behavior towards intruder males

abnormal social investigation ( J:94939 )

♂ • no decrease in the amount of time mutant males spend sniffing a female during the second exposure period is seen unlike wild-type males

homeostasis/metabolism

increased circulating testosterone level ( J:94939 )

• testosterone is elevated in young males (60-90 days old) but not in males older than 120 days