All Phenotypes Pde4a<tm1Mct> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pde4a^tm1Mct
targeted mutation 1, Marco Conti
MGI:3525068

Summary

3 genotypes

Allelic Composition	Pde4a^tm1Mct/Pde4a^tm1Mct
Genetic Background	B6N.129P2-Pde4a^tm1Mct/Mmucd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4a^tm1Mct mutation (2 available); any Pde4a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:304450 )

N	• RS25344-treated mice exhibit normal righting response

Allelic Composition	Pde4a^tm1Mct/Pde4a^tm1Mct
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4a^tm1Mct mutation (2 available); any Pde4a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:96125 )

N	• mice respond to isoproterenol in the same way as wild-type mice do

Allelic Composition	Pde4a^tm1Mct/Pde4a^tm1Mct
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4a^tm1Mct mutation (2 available); any Pde4a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:106828 )

N	• response to LPS and thioglycollate is similar to that in wild-type mice

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